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Related Experiment Video

Updated: May 29, 2026

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
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Exploring an integrated group psychotherapy-exercise program for multiple sclerosis: a non-randomized pilot study.

Adela Abelovska1, Renata Malinova2,3, Lucie Sucha2

  • 1University of New York in Prague, Londynska 41, Prague, 120 00, Czechia.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 27, 2026
PubMed
Summary
This summary is machine-generated.

This pilot study found that combining psychotherapy and exercise improved quality of life and emotional health for individuals with Multiple Sclerosis (MS). Further research is needed due to study limitations.

Keywords:
AnxietyDepressionFatigueMultiple sclerosisPsychotherapySymptoms

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Area of Science:

  • Neurology
  • Psychiatry
  • Rehabilitation Medicine

Background:

  • Multiple Sclerosis (MS) significantly impacts patients' quality of life, emotional well-being, and daily functioning.
  • Comprehensive MS care necessitates addressing both physical symptoms and mental health challenges.
  • Integrating mental health interventions into MS management is crucial for holistic patient care.

Purpose of the Study:

  • To evaluate the effectiveness of a six-week group intervention, "Your Health Belongs to You," combining psychotherapy and exercise for individuals with MS.
  • To assess the intervention's impact on quality of life, emotional health, and symptom management.
  • To emphasize the role of mental health in the overall care of MS patients.

Main Methods:

  • A pilot study with a single-blind, non-randomized, prospective pragmatic design.
  • Participants were allocated to an intervention group (n=55) or a waiting-list control group (n=13).
  • The intervention involved six weekly 90-minute sessions focused on Symptoms, Emotions, and Fatigue, with assessments using HADS, ORS, GSRS, and FSS.

Main Results:

  • Significant large-effect improvements were observed in the Outcome Rating Scale (ORS).
  • Moderate reductions in depression (HADS-D) and anxiety (HADS-A) were noted.
  • High participant engagement and therapeutic alliance were reported, with a low drop-out rate.

Conclusions:

  • Integrating psychotherapy and exercise shows potential for improving well-being and functioning in individuals with MS.
  • Findings suggest the importance of addressing mental health within MS management strategies.
  • Further randomized trials with larger, balanced groups and extended follow-up are recommended to confirm these preliminary results.