Related Experiment Video
Updated: May 29, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Caregivers' knowledge, attitudes, and practices regarding postpartum depression: a cross-sectional study
Cimei Li1, Hui Yang2, Jingjing Bi1
1Department of Obstetrics, East District Hospital, Xinxiang Central Hospital, Xinxiang, 453000, Henan, People's Republic of China.
Postpartum depression (PPD) is a prevalent psychiatric condition with significant implications for maternal and infant health. However, the role of caregivers in its management remains underexplored, particularly regarding their specific knowledge, attitudes, and practices (KAP). To address this gap, this study aimed to quantify KAP levels regarding PPD among caregivers. This cross-sectional study collected 503 surveys from primary caregivers of postpartum women in Henan, China, using a validated questionnaire between November 2024 and February 2025. Multivariable logistic regression was performed to identify factors associated with KAP outcomes, while structural equation modeling (SEM) was applied to explore the interrelationships among KAP dimensions. The results showed that mean knowledge, attitude, and practice scores were 10.63 ± 3.36 (possible range: 0-26), 38.31 ± 4.80 (possible range: 9-45), and 30.28 ± 6.49 (possible range: 8-40), respectively. Multivariable logistic regression showed that lack of access to professional psychological counseling was associated with poorer knowledge, while higher knowledge and more positive attitudes were significantly associated with proactive caregiving practices (all P < 0.001). SEM demonstrated that knowledge had significant direct effects on attitude (β = 0.300, P < 0.001) and practice (β = 0.217, P < 0.001), while attitude had a strong direct effect on practice (β = 0.703, P < 0.001). In conclusion, caregivers demonstrated limited knowledge but relatively positive attitudes and practices regarding PPD. Targeted educational interventions and improved access to psychological support may help enhance caregiver knowledge and support for postpartum mental health.
Postpartum depression (PPD) is a prevalent psychiatric condition with significant implications for maternal and infant health. However, the role of caregivers in its management remains underexplored, particularly regarding their specific knowledge, attitudes, and practices (KAP). To address this gap, this study aimed to quantify KAP levels regarding PPD among caregivers. This cross-sectional study collected 503 surveys from primary caregivers of postpartum women in Henan, China, using a validated questionnaire between November 2024 and February 2025. Multivariable logistic regression was performed to identify factors associated with KAP outcomes, while structural equation modeling (SEM) was applied to explore the interrelationships among KAP dimensions. The results showed that mean knowledge, attitude, and practice scores were 10.63 ± 3.36 (possible range: 0-26), 38.31 ± 4.80 (possible range: 9-45), and 30.28 ± 6.49 (possible range: 8-40), respectively. Multivariable logistic regression showed that lack of access to professional psychological counseling was associated with poorer knowledge, while higher knowledge and more positive attitudes were significantly associated with proactive caregiving practices (all P < 0.001). SEM demonstrated that knowledge had significant direct effects on attitude (β = 0.300, P < 0.001) and practice (β = 0.217, P < 0.001), while attitude had a strong direct effect on practice (β = 0.703, P < 0.001). In conclusion, caregivers demonstrated limited knowledge but relatively positive attitudes and practices regarding PPD. Targeted educational interventions and improved access to psychological support may help enhance caregiver knowledge and support for postpartum mental health.
Related Concept Videos
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Parental Care
Relationship with Parents: Attachment
Attachment Styles
Long-term Depression
Depression: Overview