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Prevalence and Morphometric Analysis of Coronary High Take-off in a Korean Cadaveric Population

Jiin Kim1, Seung Ok Nam2, Young-Suk Cho3

  • 1Department of Medical Sciences 3rd Grade, Chonnam National University Medical School, Hwasun, Korea.

Korean Circulation Journal
|May 28, 2026
PubMed

Insights

Coronary high take-off, an abnormal origin of coronary arteries, affects 19.5% of right coronary arteries and 16.4% of left coronary arteries in Koreans. This study provides crucial morphometric data for percutaneous coronary intervention planning.

Area of Science:

  • Cardiovascular Anatomy
  • Interventional Cardiology

Background:

  • Coronary high take-off, defined as coronary origin above the sinotubular junction (STJ), is a significant anatomical variation.
  • Limited comprehensive morphometric data exists for coronary ostia in the Korean population.
  • Understanding these variations is crucial for transcatheter interventions like percutaneous coronary intervention (PCI).

Purpose of the Study:

  • To determine the prevalence of coronary high take-off in Korean adults.
  • To measure coronary ostial height and diameter in a Korean cadaveric cohort.
  • To provide essential anatomical data for guiding interventional procedures.

Main Methods:

  • Cadaveric analysis of 128 adult Korean hearts (2018-2024).
  • Measurement of ostial height relative to the STJ using digital Vernier calipers.
  • Assessment of ostial diameter along the vertical axis; statistical analysis included t-tests and Pearson correlation.

Main Results:

  • Mean ostial heights were -1.70±3.81 mm (RCA) and -1.72±3.78 mm (LCA).
  • Prevalence of high take-off was 19.5% for RCA and 16.4% for LCA.
  • Mean ostial diameters were 4.32±1.24 mm (RCA) and 4.61±0.98 mm (LCA), with no significant sex or laterality differences.

Conclusions:

  • This study presents the first detailed coronary ostial morphometric data in Koreans.
  • A notable prevalence of coronary high take-off was observed (19.5% RCA, 16.4% LCA).
  • Findings are vital for optimizing preprocedural planning in catheter-based interventions for Korean patients.
Abstract

Keywords:
Anatomic variationCadaverCoronary vesselsRepublic of KoreaSinus of Valsalva

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