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Weightbearing CT Reveals No Anatomical Features Associated With Ligamentous Lisfranc Injuries: A Matched Case-Control
Wolfram Grün1,2,3, Enrico Pozzessere1, Emily J Luo1
1Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Foot & Ankle International
|May 28, 2026
Summary
Weightbearing computed tomography (WBCT) did not find anatomical differences in the Lisfranc joint complex associated with ligament injuries. These findings challenge previous theories and highlight the importance of 3D imaging for midfoot evaluation.
Area of Science:
- Orthopedic surgery
- Radiology
- Biomechanics
Background:
- Previous studies suggested anatomical variations in the Lisfranc joint complex may predispose individuals to ligamentous injuries.
- These associations were primarily based on 2D imaging or post-injury assessments.
- Weightbearing computed tomography (WBCT) offers 3D evaluation under physiologic load for a more accurate assessment.
Purpose of the Study:
- To reassess proposed anatomical associations with ligamentous Lisfranc injuries using WBCT.
- To compare WBCT scans of injured feet with uninjured controls to identify specific anatomical features.
Main Methods:
- Retrospective matched case-control study of 34 patients with Lisfranc injuries and 34 controls.
- WBCT scans of uninjured contralateral feet were analyzed.
- Measurements included second metatarsal (M2) length, mortise depths, foot length, and alignment parameters.
Main Results:
- No significant differences were found in M2 length, medial/lateral mortise depths, or foot alignment parameters between groups.
- A nominal difference in the sagittal first tarsometatarsal angle did not persist after correction.
- High intraobserver and moderate-to-excellent interobserver reliability were noted for measurements.
Conclusions:
- WBCT did not reveal consistent anatomical associations between Lisfranc injuries and specific features of the second metatarsal, mortise morphology, or foot alignment.
- These results challenge prior hypotheses regarding anatomical predispositions to Lisfranc injuries.
- Standardized, weightbearing 3D imaging is valuable for midfoot anatomy evaluation.
