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Related Concept Videos

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure (CHF).
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic illness...
Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
Chronic Obstructive Pulmonary Disease-V: Nursing Management01:30

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment
Methods of Documentation II: POMR01:26

Methods of Documentation II: POMR

The Problem-Oriented Medical Record (POMR) revolutionized medical record-keeping by introducing a systematic approach focusing on the patient's problems rather than merely listing symptoms. Dr. Lawrence Weed's introduction of this method in the 1960s marked a significant advancement in medical documentation. The POMR framework consists of four key components: the database, problem list, plan of care, and progress notes.
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.

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Related Experiment Video

Updated: May 29, 2026

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow
09:04

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

The PFAS roadmap-Navigating a path together to improved management.

Lokesh P Padhye1,2,3,4,5, Melanie Kah6,5, Erin M Leitao7,8,5

  • 1The New York State Center for Clean Water Technology, Stony Brook University, Stony Brook, NY 11794, United States of America.

Sustainability Science and Technology
|May 28, 2026
PubMed
Summary
This summary is machine-generated.

Managing per- and polyfluoroalkyl substances (PFAS) requires a holistic, multidisciplinary approach. This roadmap outlines expert recommendations for addressing PFAS challenges across their entire lifecycle, from source to destruction.

Keywords:
PFASPFAS alternativesPFAS analysisPFAS fatePFAS managementPFAS monitoringPFAS treatment

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Watershed Planning within a Quantitative Scenario Analysis Framework
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Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

Related Experiment Videos

Last Updated: May 29, 2026

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow
09:04

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

Watershed Planning within a Quantitative Scenario Analysis Framework
12:44

Watershed Planning within a Quantitative Scenario Analysis Framework

Published on: July 24, 2016

Area of Science:

  • Environmental Science
  • Environmental Chemistry
  • Toxicology

Background:

  • Per- and polyfluoroalkyl substances (PFAS) are diverse, persistent environmental contaminants with significant health concerns.
  • Despite extensive research, effective PFAS management remains challenging due to their ubiquitous nature and properties like persistence and potential toxicity.

Purpose of the Study:

  • To provide a comprehensive roadmap for PFAS management by synthesizing expert perspectives.
  • To identify critical knowledge gaps and recommend science and technology advancements for addressing PFAS challenges.

Main Methods:

  • A multidisciplinary roadmap featuring 15 topics from world-renowned researchers and practitioners.
  • Analysis of the entire PFAS lifecycle, including sources, fate, monitoring, regulation, remediation, and destruction.

Main Results:

  • The roadmap covers diverse facets of PFAS issues, offering an overview of the current knowledge status.
  • Highlights key themes such as monitoring, fate prediction, source control, and remediation strategies (capture and destruction).

Conclusions:

  • Numerous scientific and technological advancements show promise for PFAS management.
  • No single solution exists; multifaceted strategies and sustained collaboration among researchers, policymakers, industry, and communities are essential for long-term success.