Related Experiment Video
Updated: May 29, 2026

Operating and Biocontainment Procedures of a Facility for Laboratory Mice with a Natural Microbiome: Immunophenotyping Procedure
Published on: December 13, 2024
How Forming a Department-Specific Employee Safety Team Impacted Mitigating Risk and Improving the Safety Culture in
Sumit Ghosh1, Samantha Parsons1, Joshua Cano1
1Department of Research Safety, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Introduction:
Laboratory staff working in animal facilities face occupational risks beyond biological and chemical hazards. Organizations working with hazardous agents and animals must protect staff by developing safety programs focusing on risk reduction and fostering a positive safety culture.
Methods:
At the Abigail Wexner Research Institute at Nationwide Children's Hospital, we formed a department-specific employee safety team tasked with rolling out the Employee Safety Bundle (ESB). The ESB outlines practices and tools to prevent incidents and ensure a safe work environment. This program requires departments with frequent Occupational Safety and Health Administration recordable incidents to develop a Quantitative Risk Assessment framework. The ESB components assist with reducing the overall risks in each area by developing procedure-specific risk mitigations. Additionally, the department-specific employee safety team must develop initiatives to improve the overall safety culture within the department.
Results:
The quantitative risk assessment tool helped us identify the high-risk areas within our animal resources core (ARC) facility. We then utilized the hierarchy of controls to develop risk mitigation plans and decrease the overall risk score in each area within the ARC facility. Additionally, this program requires annual re-evaluation and a focus on continuous improvement that has helped the animal facility reduce injuries, increase near-miss reporting, and improve the safety culture.
Conclusion:
This risk score-based framework has evolved into a more holistic risk mitigation system that involves department staff members, senior leadership, safety, and other subject matter experts working together to improve the operations within an animal facility.
Related Concept Videos
Toxicity Testing in Animals
Hazard Analysis and Critical Control Points (HACCP)
Personal Protective Equipment
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution itself.
Interdisciplinary Care: The Health Care Team-II
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
