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Related Experiment Video

Updated: May 29, 2026

Fractionation of Lignocellulosic Biomass using the OrganoCat Process

Fractionation of Lignocellulosic Biomass using the OrganoCat Process

Published on: June 5, 2021

Precision Lignocellulosic Biorefinery: Process Regulation From Corn Stover to Products.

Xue-Cheng Lin^1,2, Lan Wang^1,2, Tai-Ran Pang¹

¹State Key Laboratory of Biopharmaceutical Preparation and Delivery, Beijing Key Laboratory of Biomass Refining Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|May 28, 2026

Summary

This study introduces a whole-process regulation strategy for corn stover biorefining, enhancing cellulose conversion and lignin valorization. This precision biorefinery approach increases revenue by 36.7% through optimized fractionation and component utilization.

Keywords:

biorefinery cellulose nanocrystal fermentable sugar lignin protection whole‐process regulation

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Area of Science:

Biomass Valorization
Sustainable Chemistry
Chemical Engineering

Background:

Lignocellulosic biorefineries are key to sustainable industrial practices but face challenges from component cross-interference.
Effective regulation strategies are needed throughout the entire biorefining process, not just during pretreatment.

Purpose of the Study:

To develop a whole-process regulation strategy for corn stover biorefining.
To address cross-interference issues between cellulose, hemicellulose, and lignin.
To enable directed valorization of all biomass components.

Main Methods:

Mechanical fractionation to separate corn stover into short and long fibers.
Methanol treatment during steam explosion to control lignin condensation in short fibers.
Carbon quantum dot enhancement during enzymatic hydrolysis of short fibers.
Two-stage selective enzymatic hydrolysis for long fibers to produce cellulose nanocrystals.

Main Results:

Optimized cellulose conversion and mild lignin depolymerization for epoxy resins from short fibers.
Production of high-crystallinity cellulose nanocrystals from long fibers.
A 36.7% revenue increase compared to an unregulated process was demonstrated via techno-economic analysis.

Conclusions:

The developed whole-process regulation strategy enables precision biorefining by guiding fractionation based on biomass heterogeneity.
This approach ensures compatibility between biomass attributes, process conditions, and product specifications.
The innovations have been industrially validated, demonstrating practical applicability.