Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Corrigendum to "Biological variability of lipoprotein-associated phospholipase A<sub>2</sub> activity in healthy individuals" [Clin. Biochem. 50 (2017) 347-349].

Clinical biochemistry·2026

Same author

Urine Mast Cell Mediator Levels in the Pediatric Population with and without Allergic Disease Stratified by Age and Gender: A Novel Diagnostic Insight.

Allergy·2026

Same author

Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial.

Clinical chemistry·2026

Same author

Tumor metrics imaging core labs: primer for radiologists.

Abdominal radiology (New York)·2026

Same author

Abstracts from the 2025 ADLM Preanalytical Phase Conference-Advancing Preanalytics: From Innovative Breakthroughs to Practical Applications.

The journal of applied laboratory medicine·2026

Same author

Method Validation of Dipeptidyl Peptidase 3 Assay.

The journal of applied laboratory medicine·2025

Same journal

Syphilis Serology and Antiphospholipid Antibodies: Bidirectional Reactivity Testing across Clinical and Control Samples.

The journal of applied laboratory medicine·2026

Same journal

Commentary on Unclear Bicarbonate Results in a Multiple Myeloma Patient with Hyperproteinemia.

The journal of applied laboratory medicine·2026

Same journal

Inconsistency of the FIB-4 Score in Hospitalized Patients.

The journal of applied laboratory medicine·2026

Same journal

Unclear Bicarbonate Results in a Multiple Myeloma Patient with Hyperproteinemia.

The journal of applied laboratory medicine·2026

Same journal

Current State and Needs of Clinical Laboratories in Selected Countries in Africa.

The journal of applied laboratory medicine·2026

Same journal

A Dynamic, Continuous Model for Age-Specific Anemia Classification in Children and Non-Pregnant Women.

The journal of applied laboratory medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 29, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Published on: November 30, 2015

Feasibility of Capillary Self-Collected Blood Specimens for Routine Outpatient Laboratory Testing.

Chelsea B Swartchick¹, Rachana Gurudu¹, Nathanael S Lexvold¹

¹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, United States.

The Journal of Applied Laboratory Medicine

|May 28, 2026

Summary

This summary is machine-generated.

Capillary self-collection (CSC) devices offer a convenient at-home blood collection method. However, potassium, bicarbonate, and glucose stability in CSC serum requires careful consideration during transport and testing.

More Related Videos

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Related Experiment Videos

Last Updated: May 29, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Published on: November 30, 2015

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Area of Science:

Clinical Chemistry
Point-of-Care Testing
Patient-Reported Outcomes

Background:

Capillary self-collection (CSC) devices enable at-home blood sample collection, potentially reducing clinic visits.
Evaluating patient experience and analytical performance of CSC devices is crucial for adoption.

Purpose of the Study:

Assess patient experience with commercial CSC devices.
Identify common laboratory test groupings to minimize appointments.
Evaluate the analytical performance of CSC samples for key laboratory tests.

Main Methods:

User experience evaluated for three CSC devices.
Clinical feasibility assessed by comparing CSC and venipuncture (VP) serum samples.
Analyzed stability of CSC samples under simulated shipping conditions (delayed processing, temperature extremes).

Main Results:

Patients found CSC devices easy to use and painless.
Immediate processing showed minimal clinical differences (potassium, bicarbonate).
Delayed processing (48h room temp) revealed differences in potassium, bicarbonate, and glucose.
High temperature (40°C) for 48h impacted most analytes except creatinine, lipids, PSA, and thyroid cascade.

Conclusions:

Potassium, bicarbonate, and glucose demonstrate limited stability in CSC serum at room temperature.
CSC serum is a viable option, but requires analyte-specific stability assessment and controlled transportation.