Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Single-Axon-Resolution Imaging of Peripheral Nerve Injury Response in Mice Using an Optical Window Implant.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Cross-Sectional and Longitudinal Associations Between Weight Perception and Cardiometabolic Health Among Adolescents Followed Into Emerging Adulthood.

Preventing chronic disease·2026
Same author

An Updated Comprehensive Management Algorithm for Anterior and Lateral Spontaneous Cerebrospinal Fluid Leaks.

Neurosurgery·2026
Same author

Modified Endoscopic Sphenopalatine Artery Ligation Technique Reduces Persistent Epistaxis.

The Laryngoscope·2026
Same author

Trends in emotional distress among childhood, adolescent, and young adult (CAYA) cancer survivors: A decade-long study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

Response to "Comment on 'Dupilumab Beyond the Airway: Decreased Morbidity in a Real-World Analysis'".

International forum of allergy & rhinology·2026

Related Experiment Video

Updated: May 29, 2026

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation
03:58

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

Published on: August 2, 2024

Wearable Real-Time Translation in Rhinology: A Comparative Study of Accuracy and Efficiency

Emma J Anisman1, Nickolas Pudik1, Laura Palacio-Morales1

  • 1Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

International Forum of Allergy & Rhinology
|May 28, 2026
PubMed
Summary

No abstract available in PubMed .

Related Experiment Videos

Last Updated: May 29, 2026

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation
03:58

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation

Published on: August 2, 2024