Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Parathyroid Glands

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Management of Medullary Thyroid Cancer: A Review.

Annals of surgical oncology·2026

Same author

Radiofrequency ablation for nodal recurrence in papillary thyroid carcinoma.

American journal of surgery·2026

Same author

Patient-Reported Outcomes Across Treatment Strategies in Papillary Thyroid Microcarcinoma: A Meta-Analysis.

JAMA otolaryngology-- head & neck surgery·2025

Same author

Short-term outcomes in radiofrequency ablation for the primary treatment of T1N0M0 papillary thyroid carcinomas.

American journal of surgery·2025

Same author

Quality of Life Following Thermal Ablation of Benign Thyroid Nodules: A Systematic Review and Meta-Analysis.

Thyroid : official journal of the American Thyroid Association·2025

Same author

Patient preferences in papillary thyroid microcarcinoma management are driven by aversion toward complications rather than treatment pathway.

Surgery·2025

Search research articles

Related Experiment Video

Updated: May 29, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Predictive Value of Intraoperative Parathyroid Hormone Levels via Central vs Peripheral Sampling.

Stephanie I Paz¹, Seth Rabinowitz¹, Douglas J Turner²

¹University of Maryland School of Medicine, Baltimore, MD, USA.

The American Surgeon

|May 28, 2026

Summary

The Rome criteria for intraoperative parathyroid hormone (ioPTH) monitoring during parathyroidectomy offer superior diagnostic accuracy compared to Miami criteria. Both internal jugular vein and peripheral sampling methods are effective, with Rome criteria showing better results.

Keywords:

intraoperative parathyroid hormone parathyroidectomy primary hyperparathyroidism

More Related Videos

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Related Experiment Videos

Last Updated: May 29, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

Area of Science:

Endocrinology
Surgical Oncology
Clinical Diagnostics

Background:

Intraoperative parathyroid hormone (ioPTH) monitoring is crucial for assessing adequate parathyroidectomy.
Existing criteria, such as Miami and Rome, guide ioPTH interpretation.
Sampling can be performed peripherally or via the internal jugular vein (IJ).

Purpose of the Study:

To compare the diagnostic performance of the Miami and Rome criteria for ioPTH monitoring.
To evaluate the effectiveness of internal jugular vein (IJ) versus peripheral blood sampling during parathyroidectomy.

Main Methods:

Retrospective cohort study of 201 patients undergoing parathyroidectomy for primary hyperparathyroidism (2023-2025).
Comparison of Miami and Rome criteria application.
Analysis of ioPTH levels from IJ (n=139) and peripheral (n=62) sampling sites.

Main Results:

Overall 92.5% of patients achieved normocalcemia at 6 months.
Rome criteria demonstrated higher success rates (92.8% IJ, 91.9% peripheral) compared to Miami criteria (85.6% IJ, 83.9% peripheral).
IJ sampling showed slightly higher specificity for the Miami criterion.

Conclusions:

The Rome criteria exhibit superior diagnostic properties for ioPTH monitoring in parathyroidectomy.
Both IJ and peripheral sampling are viable, with comparable performance across criteria.
Rome criteria are recommended for improved ioPTH monitoring accuracy.