CHA2DS2-VA Score Can Be Used to Predict In-Hospital Mortality in Patients with Acute Aortic Dissection.

Area of Science:

• Cardiology
• Vascular Surgery

Background:

• The CHA2DS2-VA score is established for predicting thromboembolism in atrial fibrillation.
• Its prognostic value in cardiovascular diseases is recognized, but its impact on acute aortic dissection (AAD) mortality is unknown.

Purpose of the Study:

• To investigate the association between the CHA2DS2-VA score and in-hospital mortality in patients diagnosed with AAD.

Main Methods:

• A retrospective cohort study of 113 patients surgically treated for AAD.
• CHA2DS2-VA scores were calculated for all patients.
• In-hospital mortality was recorded and analyzed in relation to CHA2DS2-VA scores.

Main Results:

• In-hospital mortality occurred in 27.5% of AAD patients.
• Mortality rates increased with higher CHA2DS2-VA scores (7% for score 1 to 53% for score ≥ 4).
• Age, CHA2DS2-VA score (OR 2.19), and hs-CRP independently predicted mortality. A CHA2DS2-VA cutoff of 3 showed 80.5% sensitivity and 78.6% specificity for mortality.

Conclusions:

• The CHA2DS2-VA score is an independent predictor of in-hospital mortality in AAD patients.
• This score demonstrates potential as a valuable prognostic marker for AAD management.