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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...

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Related Experiment Video

Updated: May 29, 2026

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management
08:50

Fabrication and Characterization of a Conformal Skin-like Electronic System for Quantitative, Cutaneous Wound Management

Published on: September 2, 2015

Bionic Cooling Skin for Infected Wound Healing.

Shuo Shi1, Huiqun Zhou2, Yang Ming1

  • 1Joint Research Centre for Fiber Innovations and Renewable Materials, School of Fashion and Textiles, The Hong Kong Polytechnic University, Hong Kong S.A.R, 999077, People's Republic of China.

Nano-Micro Letters
|May 28, 2026
PubMed
Summary
This summary is machine-generated.

A novel bionic cooling skin dressing promotes infected wound healing. This advanced material mimics natural skin, offering antibacterial properties and reducing wound temperature for improved patient outcomes.

Keywords:
Bionic skinBreathableJanus structureNanofibersWound healing

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Last Updated: May 29, 2026

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Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device
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Chessboard-like Burn Wound Healing Model of Mice Based on Digital Heating Device

Published on: December 27, 2024

Area of Science:

  • Biomaterials Science
  • Wound Healing Research
  • Nanotechnology

Background:

  • Infected wounds present significant clinical challenges, often leading to delayed healing and severe complications.
  • Current wound dressings rarely integrate comprehensive protective, comfortable, and antibacterial functionalities.
  • Effective management of infected wounds is crucial for preventing adverse health outcomes.

Purpose of the Study:

  • To develop an innovative bionic cooling skin for enhanced infected wound management.
  • To create a wound dressing with integrated antibacterial properties and a cooling effect.
  • To investigate the wound healing mechanisms promoted by the novel dressing.

Main Methods:

  • Fabrication of a hierarchical nanofiber-based bionic skin using solvent welding technology.
  • Integration of single-sided metal-organic frameworks (MOFs) for visible light-responsive reactive oxygen species (ROS) generation.
  • Characterization of mechanical properties, air/moisture permeability, and thermal regulation capabilities.

Main Results:

  • The bionic skin demonstrated excellent mimicry of natural skin's mechanical properties (σmax = 21.6 MPa; εmax = 54%) and high permeability.
  • The dressing exhibited effective antibacterial activity through ROS generation, confirmed by gene analysis of wound healing.
  • A significant reduction of 4°C in local wound temperature was observed under sunlight exposure due to high mid-infrared emissivity.

Conclusions:

  • The developed bionic cooling skin offers a promising solution for infected wound management.
  • This advanced dressing integrates superior protective, antibacterial, and thermal regulation functions.
  • The study advances wound care strategies and biomedical material design for improved healing efficacy and patient comfort.