Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Research02:20

Longitudinal Research

Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ethical Challenges in the Delivery of Family-Centered Nursing Care.

Journal of family nursing·2026
Same author

Noninvasive Respiratory Support for Adult Patients with Acute Respiratory Failure. An Official American Thoracic Society Clinical Practice Guideline.

American journal of respiratory and critical care medicine·2026
Same author

A Qualitative Multicenter Study of Participant Experiences With an App-Based Mindfulness Intervention (Lift 2) for Critical Illness Survivors.

Critical care explorations·2026
Same author

A Modular High-Parameter Flow Cytometry Framework: Pre-Analytical Optimization and Validation for Clinical Research.

Cytometry. Part A : the journal of the International Society for Analytical Cytology·2026
Same author

Remotely delivered resistance training program in adult sarcoma survivors: a pilot study.

BMC cancer·2026
Same author

Advancing palliative care in cardiac arrest and cardiogenic shock: identifying evidence gaps and future research priorities.

Frontiers in cardiovascular medicine·2026
Same journal

Less Can Be More by Circulating Tumor DNA Use in ERBB2-Positive Breast Cancer.

JAMA oncology·2026
Same journal

Long-Term Outcomes in Patients With Recurrent Ovarian Cancer and Exceptional Response to PARP Inhibitors.

JAMA oncology·2026
Same journal

Three-Body Problem at Digital Frontiers.

JAMA oncology·2026
Same journal

Neoadjuvant Paclitaxel, Trastuzumab, and Pertuzumab for Stage II to III, ERBB2-Positive Breast Cancer: A Secondary Analysis of the DAPHNe Trial.

JAMA oncology·2026
Same journal

Survival in the SONIA Trial-Reply.

JAMA oncology·2026
Same journal

Second Primary Malignant Neoplasms After T-Cell-Engaging Bispecific Antibody Therapy: A Systematic Review and Meta-Analysis.

JAMA oncology·2026
See all related articles

Related Experiment Video

Updated: May 29, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Longitudinal Risk for Suicidal Self-Directed Violence Among Veterans With Cancer.

Donald R Sullivan1,2,3, Natalie Disher4, William E Rosa5

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Oregon Health & Science University, Portland.

JAMA Oncology
|May 28, 2026
PubMed
Summary
This summary is machine-generated.

Veterans with cancer face persistent risks of suicidal self-directed violence (SSDV), with specific subgroups like younger or Asian veterans showing higher rates. Comprehensive tracking of all suicidal behaviors is crucial for tailored prevention strategies in cancer care.

Related Experiment Videos

Last Updated: May 29, 2026

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Area of Science:

  • Oncology
  • Psychiatry
  • Veterans Health

Background:

  • Patients with cancer have higher rates of suicidal self-directed violence (SSDV) than the general population.
  • Understanding longitudinal risks and risk factors for SSDV among veterans with cancer is critical for improving screening and prevention.

Purpose of the Study:

  • To assess longitudinal risks and methods for SSDV among veterans with cancer.
  • To identify associated risk factors for SSDV to enhance screening and prevention strategies.

Main Methods:

  • A national cohort study of veterans diagnosed with invasive solid or hematologic cancer between January 2014 and December 2023.
  • Data were sourced from oncology and suicide registries and the Veterans Health Administration (VA).
  • Multivariable Cox proportional hazards models were used to estimate adjusted hazard ratios (aHRs) for SSDV risk factors.

Main Results:

  • The study identified 2400 SSDV events (1%) among 292,271 veterans, with poisoning being the most common method (26%).
  • Elevated SSDV probabilities were observed in veterans with specific cancers (CNS, pancreas, head and neck, liver, thyroid), severe frailty, advanced cancer, chronic mental illness, and high pain scores.
  • Increased SSDV hazards were noted for Asian veterans, unmarried veterans, and those with CNS or head and neck cancers compared to White veterans and those with lung cancer, respectively. Risk remained elevated for younger, unmarried, and certain cancer subgroups even five years post-diagnosis.

Conclusions:

  • Veterans with cancer are at significant risk for SSDV that can persist for years after diagnosis.
  • Subgroups such as younger veterans, Asian veterans, and those with thyroid cancer represent previously overlooked high-risk populations.
  • Systematic tracking of all suicidal behaviors, not solely fatal attempts, is essential for developing tailored screening and prevention strategies within cancer care.