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Multidisciplinary Consensus Statement for Appropriate Evaluation and Workup of Sinonasal Masses
Nyall R London1,2,3,4, Jerlon Chiu2, Neal S Akhave5
1Sinonasal and Skull Base Tumor Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
JAMA Otolaryngology-- Head & Neck Surgery
|May 28, 2026
Summary
Suboptimal nasal mass evaluation can harm patients. This expert consensus provides clear recommendations for diagnosis and workup, aiming to improve patient outcomes by avoiding common pitfalls.
Area of Science:
- Otolaryngology
- Rhinology
- Head and Neck Surgery
Background:
- Suboptimal practices in evaluating nasal masses can negatively impact patient outcomes.
- There is a need for standardized, evidence-based recommendations to address common pitfalls in clinical management.
Purpose of the Study:
- To establish expert consensus recommendations for the evaluation and workup of nasal masses.
- To optimize management strategies and improve patient outcomes by avoiding diagnostic and therapeutic errors.
Main Methods:
- A systematic literature review was performed from 1990 to 2025 to identify guideline gaps.
- A modified Delphi approach was utilized for a survey of 25 multidisciplinary experts in otolaryngology, head and neck surgery, rhinology, neurosurgery, and medical oncology.
- The consensus process involved generating and evaluating 23 statements on nasal mass evaluation and workup.
Main Results:
- Twenty-five multidisciplinary experts participated in the consensus survey.
- Twenty-three consensus statements were formulated and evaluated.
- Twenty-two statements achieved expert consensus after initial evaluation or revision, covering initial evaluation, biopsy, imaging, and pathologic assessment.
Conclusions:
- This expert consensus statement offers guidance for physicians on the proper evaluation and workup of nasal masses.
- Adherence to these recommendations can help avoid common pitfalls and optimize patient management.
- The consensus aims to ultimately improve patient outcomes through standardized and effective practices.
