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Efficacy of an e-Learning Module on Endocrine Disruptors for Family Medicine Residents: Matched Before-And-After
Mathieu Diallo1, Lionel Moulis2,3, Maha Badreddine4
1University Department of General Practice, Faculty of Medicine, Université de Montpellier, Montpellier, Occitanie, France.
JMIR Formative Research
|May 28, 2026
Summary
An innovative e-learning module significantly improved family medicine residents' knowledge and behaviors regarding endocrine-disrupting chemicals (EDCs). This training enhances preventive care competencies for environmental health.
Area of Science:
- Environmental Health
- Medical Education
- Endocrinology
Background:
- Environmental factors contribute significantly to global mortality and chronic diseases.
- France's national health plan emphasizes training health professionals in environmental health.
- Endocrine-disrupting chemicals (EDCs) pose risks by interfering with hormonal systems.
Purpose of the Study:
- To evaluate an e-learning module's impact on resident satisfaction, knowledge, and behaviors concerning household EDCs.
- Assess the effectiveness of a novel educational intervention for primary care physicians.
Main Methods:
- A monocentric, before-and-after cohort study of first-year family medicine residents.
- Utilized an e-learning module with interactive elements, AI, videos, games, and flashcards.
- Assessed participants via pre/post questionnaires on satisfaction, knowledge, and behaviors, with statistical analysis (McNemar, t-tests).
Main Results:
- High participant satisfaction with the e-learning format and duration.
- Significant improvements in knowledge (P<.001) and self-reported preventive behaviors (P<.001).
- Post-training identification of at-risk populations and exposure sites improved, though specific EDC recognition varied.
Conclusions:
- The e-learning module effectively enhanced residents' knowledge and preventive behaviors regarding EDCs.
- Supports integrating environmental health training into medical curricula.
- Highlights the potential of e-learning for scalable interventions in primary care education.
Related Concept Videos
Endocrine Signaling
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
Hormonal Regulation
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
Hormonal Regulation
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
Intracellular Hormone Receptors
Lipid-soluble hormones diffuse across the plasma and nuclear membrane of target cells to bind to their specific intracellular receptors. These receptors act as transcription factors that regulate gene expression and protein synthesis in the target cell