Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impacts of affiliated stigma on depression and anxiety in Chinese parents of children with autism spectrum disorders: roles of parental burnout and spouse support.

BMC public health·2026
Same author

Unraveling children's mental rotation: insights from behavior and eye tracking.

Scientific reports·2026
Same author

EEG Insights into Visual Attention and Affective Prosody Processing in Children with Autism Spectrum Disorder: Examining the Theta/Alpha Ratio.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025
Same author

Social anxiety and gratitude among children left behind due to migration in western rural China.

Scientific reports·2025
Same author

Suicidal risk among Chinese parents of autistic children and its association with perceived discrimination, affiliate stigma and social alienation.

BMC psychiatry·2024
Same author

Interaction and association between multiple vitamins and social adaptability and severity of autism: A large-scale retrospective study from China.

Autism research : official journal of the International Society for Autism Research·2024

Related Experiment Video

Updated: May 31, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Resting-state EEG functional connectivity predicts autistic traits in typically developing individuals.

Muhammad Zakir Ullah1, Liu Fulin1, Dongchuan Yu2

  • 1Key Laboratory of Child Development and Learning Science of Ministry of Education, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.

Psychiatry Research. Neuroimaging
|May 28, 2026
PubMed
Summary

Lower brain connectivity in the Delta/Theta frequency bands is linked to autistic traits in typically developing adults. This electroencephalogram study highlights functional connectivity as a potential biomarker for neurodevelopmental differences.

Keywords:
Autism spectrum disorderAutistic traitsFunctional connectivityand Autism spectrum quotient

More Related Videos

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Related Experiment Videos

Last Updated: May 31, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Area of Science:

  • Neuroscience
  • Psychology
  • Biomarkers

Background:

  • Autism spectrum disorder (ASD) is viewed dimensionally, with autistic traits present across the general population.
  • Neurophysiological underpinnings of autistic traits in typically developing (TD) individuals are not well understood.
  • Understanding these correlates can inform early identification and intervention strategies.

Purpose of the Study:

  • To investigate the association between autistic traits and electroencephalogram (EEG) functional connectivity (FC) in TD adults.
  • To identify specific EEG FC metrics and frequency bands related to autistic traits.
  • To explore the relationship between FC and core ASD domains like social skills and communication.

Main Methods:

  • Collected resting-state EEG data from 88 TD adults.
  • Measured functional connectivity (PLV, WPLI, PLI) across five frequency bands.
  • Utilized multiple regression and Pearson correlation analyses between Autism Spectrum Quotient (AQ) scores and EEG FC metrics.

Main Results:

  • Lower Delta/Theta band phase locking value (PLV) connectivity significantly predicted higher autistic traits (FDR corrected p = 0.010).
  • EEG Delta/Theta band PLV connectivity showed significant correlations with social skills and communication AQ subscales.
  • These findings indicate reduced low-frequency connectivity is associated with autistic trait expression.

Conclusions:

  • EEG functional connectivity in the Delta/Theta frequency bands, particularly PLV, is associated with autistic traits in the general population.
  • Delta/Theta PLV connectivity is specifically linked to social and communication domains, core to ASD.
  • This highlights Delta/Theta PLV connectivity as a potential physiological correlate of autistic trait expression in TD individuals.