Related Experiment Video
Updated: May 31, 2026
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Bleeding patterns after replacing versus extending the use of the contraceptive implant at three years of use
Sheila K Mody1, Gennifer Kully1, Marisa C Hildebrand1
1Division of Complex Family Planning, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, San Diego, CA, United States.
Objectives:
We compared the number of bleeding days among individuals who replaced versus those who extended use of their contraception implant after three years.
Methods:
Participants reported number of bleeding days for 30 days prior to their 68 mg subdermal etonogestrel implant appointment, decided to replace or extend, and then reported number of bleeding days for 30 days after.
Results:
Comparing 23 replacers and 29 extenders, we found little difference in point estimates of bleeding days between the two groups (4.0 (IQR 0.0-7.0) and 5.0 (IQR 1.0-7.0), respectively, p = 0.85)).
Conclusion:
Neither replacing nor extending contraceptive implants at three years of use results in significant bleeding changes in the following 30 days.
Implications:
Clinicians can counsel patients that short-term bleeding patterns are not expected to change meaningfully when replacing or extended use of contraceptive implant at three years.
Related Concept Videos
01:21Intrauterine Drug Delivery Systems
01:22Birth Control Methods
01:20Proliferative Phase
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...