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Practice parameter for inborn errors of immunity: What is new in the 2025 update

Javier Chinen1, Catherine C Horner2, Jordan S Orange3

  • 1Division of Immunology, Allergy and Retrovirology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex.

The Journal of Allergy and Clinical Immunology
|May 28, 2026
PubMed
Summary

The 2025 practice parameter for inborn errors of immunity updates diagnosis and management guidelines. Key changes include newborn screening, genetic testing, and updated recommendations for treatment strategies like immunoglobulin replacement and transplantation.

Keywords:
IEIantibiotic prophylaxisgenetic testingimmunodeficiencynewborn screeningpractice parameterprecision medicinequality of life

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