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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Anthelminthic Agents01:15

Anthelminthic Agents

Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...
Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
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Related Experiment Video

Updated: May 31, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Optimising treatment options in scabies

    Drug and Therapeutics Bulletin
    |May 28, 2026
    PubMed
    Summary

    Oral ivermectin and topical permethrin cream are effective treatments for scabies in children and adults. This study compared the efficacy of these two common scabies therapies.

    Area of Science:

    • Dermatology
    • Parasitology
    • Clinical Trials

    Background:

    • Scabies is a contagious skin infestation caused by the mite Sarcoptes scabiei.
    • Classic scabies affects millions worldwide, necessitating effective and accessible treatments.
    • Both oral ivermectin and topical permethrin cream are widely used for scabies management.

    Purpose of the Study:

    • To compare the efficacy of oral ivermectin versus 5% permethrin cream in treating classic scabies.
    • To evaluate treatment outcomes in a large, multicentre, blinded, cluster-randomised clinical trial setting.

    Main Methods:

    • A multicentre, assessor-blinded, cluster-randomised clinical trial was conducted.
    • Participants included children and adults diagnosed with classic scabies.
    Keywords:
    Drug-Related Side Effects and Adverse ReactionsHealth Care Quality, Access, and Evaluation

    Related Experiment Videos

    Last Updated: May 31, 2026

    The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
    11:39

    The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

    Published on: July 11, 2013

  • Treatment arms involved either oral ivermectin or 5% permethrin cream.

    • Main Results:

    • Both oral ivermectin and 5% permethrin cream demonstrated high efficacy in treating classic scabies.
    • The study provides robust comparative data on these two treatment modalities.
    • No significant differences in cure rates were observed between the two treatment groups.

    Conclusions:

    • Oral ivermectin and 5% permethrin cream are both effective first-line treatments for classic scabies.
    • The choice between oral ivermectin and topical permethrin may depend on patient factors and clinical context.
    • Further research could explore long-term outcomes and resistance patterns.