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Updated: May 31, 2026

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury
Published on: October 21, 2017
Miscellaneous Equine Liver Conditions
Sandra D Taylor1, Stephanie N Brooks1
1Department of Veterinary Clinical Sciences, Purdue University, 625 Harrison Street, West Lafayette, IN 47907, USA.
None:
Miscellaneous equine liver conditions not covered in other chapters include chronic active hepatitis, Tyzzer's disease, seasonal idiopathic hepatitis, neoplasia, and idiopathic persistent hyperbilirubinemia. Chronic active hepatitis refers to inflammatory and fibrotic liver disease with an unknown cause. Treatment is aimed at reducing inflammation. Tyzzer's disease is caused by Clostridium piliforme infection and causes acute necrotizing hepatitis in foals. Successful treatment with antimicrobial therapy and supportive care is rare. Seasonal idiopathic hepatitis is a winter disease of Midwestern horses. The cause is unknown but the prognosis is excellent with supportive care. Primary hepatic neoplasia and idiopathic persistent hyperbilirubinemia are rare.
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