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Updated: May 31, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
Published on: September 20, 2018
Stimulus-responsive nuclear moonlighting of plant metabolic enzymes rewires chromatin
Guiyu Xiao1, Jisen Zhang1, Qiutao Xu1
1Guangxi Sugarcane Bio-breeding Laboratory, State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, College of Agriculture, Guangxi University, Nanning 530004, China.
Abstract:
Traditionally viewed as cytoplasmic catalysts, plant metabolic enzymes are now known to moonlight in the nucleus. This forum article highlights emerging mechanisms by which nuclear-localized metabolic enzymes couple plant metabolic status to development and stress responses via chromatin regulation, providing a conceptual framework for metabolic-epigenetic crosstalk and future crop improvement.
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