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Updated: May 31, 2026

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Laparoscopic Minimally Invasive Approach for Left Paracaval Retroperitoneal Schwannoma.

Lorenzo Barberis1, Francesco Santullo2, Carlo Abatini3

  • 1General Surgery Department, Università Cattolica del Sacro Cuore, Rome, Italy.

Annals of Surgical Oncology
|May 28, 2026
PubMed
Summary

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Laparoscopic resection of retroperitoneal schwannomas is feasible and safe for selected patients. This approach allows for meticulous dissection near major vessels, leading to successful tumor removal and disease-free outcomes.

Area of Science:

  • Surgical Oncology
  • Gastrointestinal Surgery

Background:

  • Schwannomas are rare, typically benign nerve tumors found in the retroperitoneum.
  • Their proximity to major vascular structures complicates surgical removal.
  • Laparoscopic resection in this region is infrequently reported and technically demanding.

Purpose of the Study:

  • To report a case of laparoscopic resection of a retroperitoneal schwannoma.
  • To evaluate the feasibility and safety of this minimally invasive approach for tumors near major vessels.

Main Methods:

  • A 55-year-old male with an incidentally detected retroperitoneal mass underwent laparoscopic surgery.
  • The lesion, abutting the inferior vena cava and left renal vein, was dissected using an avascular plane.
  • Preoperative endoscopic ultrasound-guided biopsy confirmed schwannoma.

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Main Results:

  • Laparoscopic resection was completed in 200 minutes with minimal blood loss (200 mL) and no complications.
  • Pathology confirmed a 4.5 cm schwannoma with negative margins.
  • The patient recovered uneventfully and remained disease-free at 1-year follow-up.

Conclusions:

  • Laparoscopic resection of retroperitoneal schwannomas adjacent to major vasculature is achievable in specialized centers.
  • Preoperative biopsy is crucial for accurate diagnosis and surgical planning.
  • Tailoring resection based on oncologic principles ensures safe and effective treatment.