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Examining the Risk and Psychosocial Intervention for Suicidal Behavior and Death Among People With Cancer: A
Zheng Zhang1, Lifang Zhang1, Qiyue Qiu2
1First Affiliated Hospital of Henan Medical University, Xinxiang, Henan, China.
Psycho-Oncology
|May 29, 2026
Summary
Suicide risk in cancer patients is increasing. This meta-analysis found weak evidence for risk factors and no significant impact of psychosocial interventions on suicidal behavior in cancer patients.
Area of Science:
- Oncology
- Psychiatry
- Public Health
Background:
- Suicide rates among cancer patients are rising.
- Lack of integrated evidence hinders clinical decisions and research prioritization in cancer care.
- This study addresses the growing concern of suicidal behavior in individuals with cancer.
Purpose of the Study:
- To synthesize evidence on risk factors for suicidal behavior and death in cancer patients.
- To evaluate the effectiveness of psychosocial interventions for suicidal behavior in cancer patients.
- To inform clinical practice and future research in oncology and survivorship.
Main Methods:
- Comprehensive literature search across major databases (PubMed, Embase, Web of Science, Cochrane, PsycINFO) up to December 2025.
- Included 39 studies for risk factor assessment and 9 randomized controlled trials for intervention effectiveness.
- Meta-analysis to synthesize cumulative evidence on risk and intervention outcomes.
Main Results:
- A weak but statistically significant combined effect of risk factors for suicidal behavior was identified.
- No statistically significant combined effect of risk factors for suicidal death was found.
- Psychosocial interventions did not demonstrate significant changes in suicidal behavior severity compared to control groups.
Conclusions:
- Future psychosocial interventions should focus on managing depression and suicidal behavior in cancer patients.
- Preventive measures and stratification should target non-modifiable risk factors for suicidal behavior and death.
- Improved study methodologies are recommended for future research in this area.
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