Comparative Efficacy of Two Occluding Toothpastes: An 8 Weeks Randomised Control Trial.

Area of Science:

• Dentistry
• Oral Health
• Clinical Research

Background:

• Dentine hypersensitivity (DH) is a common condition affecting oral health-related quality of life.
• Effective management of DH is crucial for patient well-being.

Purpose of the Study:

• To compare the long-term clinical efficacy of a 5% calcium sodium phosphosilicate (CSPS) toothpaste and an 8% arginine/calcium carbonate toothpaste against a fluoride control for relieving dentine hypersensitivity (DH).

Main Methods:

• A 12-week, randomized, double-blind, controlled study involving adults with diagnosed DH.
• Participants used one of three toothpastes twice daily.
• Dentine hypersensitivity was assessed using Schiff Sensitivity Scale, visual analogue scale (VAS), and tactile threshold at baseline and various follow-up points.

Main Results:

• Both 5% CSPS and 8% arginine toothpastes showed statistically significant reductions in DH from baseline.
• The 5% CSPS toothpaste was significantly more effective than the control in reducing DH via Schiff sensitivity score and tactile threshold.
• The 8% arginine toothpaste also demonstrated statistically superior results compared to the control.

Conclusions:

• The 5% CSPS toothpaste offers significant benefits for DH relief, comparable to the 8% arginine toothpaste.
• Effective desensitizing toothpastes, including those with 5% CSPS or 8% arginine, can be recommended for managing dentine hypersensitivity.
• These toothpastes provide rapid and continued reduction in DH symptoms with regular use.