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Updated: May 31, 2026
Robotic-assisted Bronchoscopy Combined with Multimodal Imaging for Targeted Lung Cryobiopsies
Published on: July 19, 2024
Lymphangioleiomyomatosis with superimposed organizing pneumonia diagnosed by transbronchial lung cryobiopsy: A case
Naoko Takeuchi1, Takayuki Takimoto1,2, Mitsuhiro Moda1
1Department of Respiratory Medicine, NHO Kinki Chuo Chest Medical Center, Sakai City, Osaka, Japan.
Abstract:
Lymphangioleiomyomatosis (LAM) is a cystic lung disease characterized by rounded, thin-walled cysts uniformly distributed within normal lung parenchyma on high-resolution chest computed tomography. We report a case of diffuse cystic lung disease with multiple alveolar opacities. Transbronchial lung biopsy showed organizing pneumonia, but LAM cells were not observed. She was diagnosed with cryptogenic organizing pneumonia (COP) and treated with corticosteroid therapy. LAM was definitively diagnosed by transbronchial lung cryobiopsy about two years after completing corticosteroid therapy for COP. We reported the first case of LAM with concomitant COP.