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Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
Zoster-Like Dermatomal Eruption Following Recombinant Zoster Vaccine: A Case Report
Reem M AlZahrani1, Ahlam H Alsulami1, Zubaida H Khan1
1Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.
Abstract:
The reactivation of the varicella zoster virus (VZV) is the cause of herpes zoster (HZ), usually referred to as shingles. Once an individual has been previously infected with chickenpox, the virus stays dormant in their nervous system and may reactivate later in life, leading to HZ. HZ poses a significant burden on the healthcare system due to its high prevalence. Older adults and individuals with compromised immune function are at higher risk of viral reactivation. Vaccination against HZ is a highly effective strategy in preventing viral recurrence and its associated complications. However, recognizing rare post-vaccination zoster-like cutaneous eruptions is essential. In this report, we present a rare instance of a clinically suspected HZ-like eruption in an 85-year-old man who developed an erythematous maculopapular rash with scattered vesicular lesions on his right neck and shoulder one day after receiving a standard dosage vaccine. The patient was treated with valacyclovir for seven days. The immediate recognition of healthcare professionals is the aim of this report to promote early diagnosis and treatment.
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