Adrenal neuroblastoma presenting as lameness in a six-year-old boy: a case report

Neuroblastoma (NB) is the most lethal extracranial solid malignancy in children and presents with diverse clinical manifestations. Extra-abdominal symptoms may delay diagnosis. This case involves a previously healthy 6-year-old boy who presented with a one-month history of isolated lameness. Initial clinical examination and pelvic radiography were unremarkable. Pelvic magnetic resonance imaging demonstrated bilateral bone metastases, while abdominal imaging revealed a right adrenal mass. Surgical biopsy and histological analysis confirmed a non-amplified NMYC adrenal NB. The patient received neoadjuvant chemotherapy, complete surgical resection, and adjuvant chemotherapy. Histopathological examination confirmed a differentiating NB. The postoperative course was uneventful.