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Updated: May 31, 2026

Development of an In Vitro Assay to Quantitate Hematopoietic Stem and Progenitor Cells (HSPCs) in Developing Zebrafish Embryos
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Development of an In Vitro Assay to Quantitate Hematopoietic Stem and Progenitor Cells (HSPCs) in Developing Zebrafish Embryos

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Correction: A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental

Shintaro Imamura, Junzo Uchiyama, Eriko Koshimizu

    Plos One
    |May 29, 2026
    PubMed
    Summary

    This study corrects a previously published article. The correction ensures accurate referencing and data integrity for future research.

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    In eukaryotic DNA replication, a single-stranded DNA fragment remains at the end of a chromosome after the removal of the final primer. This section of DNA cannot be replicated in the same manner as the rest of the strand because there is no 3’ end to which the newly synthesized DNA can attach. This non-replicated fragment results in gradual loss of the chromosomal DNA during each cell duplication. Additionally, it can induce a DNA damage response by enzymes that recognize single-stranded DNA.