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Related Experiment Video

Updated: May 31, 2026

Microfluidic Picoliter Bioreactor for Microbial Single-cell Analysis: Fabrication, System Setup, and Operation

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Published on: December 6, 2013

Bamboo-Inspired bionic microfluidic Reactor: Construction and application for industrial Biocatalysis.

Quan Zhou¹, Litao Wang¹, Zijing Zhao²

¹State Key Laboratory of Efficient Production of Forest Resources, Beijing Forestry University, Beijing, PR China; The College of Forestry, Beijing Forestry University, 100083 Beijing, PR China; Beijing Key Laboratory of Efficient Synthesis of Plant Secondary Metabolites, PR China.

Bioresource Technology

|May 29, 2026

Summary

A novel, low-cost, bamboo-inspired microfluidic biocatalytic reactor was developed for efficient phytochemical conversion. This green technology offers scalable industrial applications for continuous biotransformation processes.

Keywords:

Cellulose nanofibers Delignified bamboo Enzyme immobilization Microfluidic reactor β-glucosidase

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Last Updated: May 31, 2026

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Area of Science:

Biotechnology
Materials Science
Chemical Engineering

Background:

Microfluidic biocatalytic reactors are crucial but expensive for industrial use.
There is a need for cost-effective and environmentally friendly reactor designs.

Purpose of the Study:

To develop a scalable, low-cost, and green microfluidic biocatalytic reactor using delignified bamboo.
To establish an efficient enzyme immobilization system on the bamboo platform.

Main Methods:

Utilizing delignified bamboo as a biocompatible, porous platform for enzyme immobilization.
Optimizing delignification and Schiff base coupling for enzyme attachment.
Constructing a β-glucosidase-functionalized flow reactor for continuous biotransformation.

Main Results:

Achieved 90.20% immobilization yield and 95.35% retained enzyme activity.
Demonstrated a high protein loading capacity of 1.97 U·mg⁻¹.
Obtained 87.97% substrate biotransformation rate and a 2.4-fold increase in resveratrol concentration within 1 hour.

Conclusions:

The bamboo-based reactor is simple to prepare and scalable for industrial applications.
This bionic reactor offers a cost-effective and green solution for continuous phytochemical conversion.
The developed system shows significant potential for commercial biotransformation processes.