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Updated: May 31, 2026

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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Cryo-EM structures of GPR133 from basal organisms elucidate evolutionary conservation and divergence of its

Meng-Xin Wang1, Jin Wang2, Du-Xiao Yang1

  • 1Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China.

Biochemical and Biophysical Research Communications
|May 29, 2026
PubMed

Keywords:
Activation mechanismAdhesion GPCRCryo-EMEvolutionGPR133

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