Related Experiment Video
Updated: May 31, 2026

Inducing Hairy Roots by Agrobacterium rhizogenes-Mediated Transformation in Tartary Buckwheat (Fagopyrum tataricum)
Published on: March 11, 2020
Farnesol modulated growth and pigmentation in Talaromyces sp. LRS407 via ROS-mediated UPR and RQC signaling pathways
Jiawen Ma1, Yufei Dai2, Xun Shen2
1School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, Zhejiang Province, 310018, China; Jinshan College of Fujian Agriculture and Forestry University, Fuzhou, Fujian Province, 350002, China.
Exogenous farnesol inhibits Talaromyces fungal growth and spore production. Farnesol also boosts red pigment biosynthesis via reactive oxygen species (ROS)-mediated pathways, offering insights into fungal physiology and natural pigment production.
Area of Science:
- Mycology
- Biochemistry
- Natural Products Chemistry
Background:
- Penicillium and Talaromyces species are sources of novel natural pigments.
- Research interest in these fungi is growing due to their pigment-producing capabilities.
Purpose of the Study:
- To investigate the effects of exogenous farnesol on Talaromyces sp. LRS407.
- To elucidate the molecular mechanisms underlying farnesol's impact on fungal growth and pigment production.
Main Methods:
- Treatment of Talaromyces sp. LRS407 with exogenous farnesol.
- Analysis of spore germination, production, biomass yield, and cell morphology.
- Measurement of reactive oxygen species (ROS) levels.
- Assessment of ribotoxic quality control (RQC) and unfolded protein response (UPR) pathway activation.
Main Results:
- Farnesol inhibited spore germination and production.
- Biomass yield was reduced, and morphological changes (shortened septum distance, hyper-branching) were observed.
- Red pigment biosynthesis was upregulated.
- Increased reactive oxygen species (ROS) levels were detected, alongside activation of RQC and UPR pathways.
Conclusions:
- Farnesol regulates Talaromyces fungal growth and pigmentation.
- The effects are mediated through ROS-dependent activation of RQC and UPR signaling pathways.
- Findings provide new insights into farnesol signaling and natural food pigment production in Talaromyces.
More Related Videos
04:11Pattern-Triggered Oxidative Burst and Seedling Growth Inhibition Assays in Arabidopsis thaliana
Published on: May 21, 2019
10:05Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
Published on: May 8, 2020
Related Concept Videos
Gene Regulation During Sporulation
TGF - β Signaling Pathway
Gene Regulation in Microbial Communities: Quorum Sensing
Cell Signaling in Plants