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Related Concept Videos

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Published on: December 27, 2024

Office-Based Procedures for Chronic Cough.

Mollie C Perryman1, C Blake Simpson1

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Otolaryngologic Clinics of North America
|May 29, 2026
PubMed
Summary
This summary is machine-generated.

Refractory chronic cough, caused by laryngeal hypersensitivity, can be treated with office-based procedures. These interventions offer safe and effective alternatives or additions to standard therapies for persistent cough.

Keywords:
Botulinum toxinChronic coughIn-office proceduresLaryngeal hypersensitivityNeurogenic coughSuperior laryngeal nerve blockVocal fold injection

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Area of Science:

  • Otolaryngology
  • Pulmonology
  • Neurology

Background:

  • Refractory chronic cough is a prevalent and difficult condition.
  • Laryngeal hypersensitivity is the underlying cause of this cough.
  • Current treatments may be insufficient for some patients.

Purpose of the Study:

  • To review office-based procedures for refractory chronic cough.
  • To discuss the rationale, techniques, and outcomes of these interventions.
  • To evaluate their role as adjuncts or alternatives to existing therapies.

Main Methods:

  • Review of literature on office-based interventions for chronic cough.
  • Focus on superior laryngeal nerve block, laryngeal botulinum toxin injection, and vocal fold injection augmentation.
  • Analysis of safety, cost-effectiveness, and tolerability in a clinical setting.

Main Results:

  • Superior laryngeal nerve block, botulinum toxin injection, and vocal fold injection augmentation are viable office-based options.
  • These procedures demonstrate safety and cost-effectiveness.
  • They are generally well-tolerated by patients in the clinic setting.

Conclusions:

  • Office-based procedures provide valuable treatment options for refractory chronic cough.
  • These interventions can be used alongside or instead of traditional therapies.
  • They offer a safe and effective approach for managing laryngeal hypersensitivity-related cough.