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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
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Tonsillitis II: Management

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The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

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Related Experiment Video

Updated: May 31, 2026

Meal Duration as a Measure of Orofacial Nociceptive Responses in Rodents
09:05

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Published on: January 10, 2014

Masticatory function, inflammation, and mortality after stroke: A prospective cohort study.

Wenshu Zhang1, Yu Wang, Yuli Wu

  • 1Department of Acupuncture and Rehabilitation, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.

Medicine
|May 30, 2026
PubMed
Summary

Good chewing ability (functional tooth units) is linked to lower mortality in stroke survivors. Systemic inflammation partially explains this link for all-cause mortality, suggesting chewing function is a useful prognostic marker.

Keywords:
AISIFTUNHANESSIRIinflammatory biomarkersmortalitystroke

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09:05

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A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
09:52

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Published on: August 8, 2014

Area of Science:

  • Neurology
  • Gerontology
  • Public Health

Background:

  • Stroke survivors face increased mortality risks, influenced by various health factors.
  • Masticatory function, or chewing ability, is increasingly recognized as a potential health indicator.
  • Systemic inflammation is a known contributor to adverse health outcomes, including mortality.

Purpose of the Study:

  • To investigate the association between masticatory function and all-cause and cardiovascular mortality in stroke patients.
  • To explore the mediating role of systemic inflammation in the relationship between masticatory function and mortality.
  • To determine if masticatory function can serve as a prognostic marker for stroke survivors.

Main Methods:

  • Utilized data from 1708 stroke patients (aged ≥20) from the National Health and Nutrition Examination Survey (1999-2018).
  • Assessed masticatory function using the count of functional tooth units (FTUs).
  • Employed Cox regression and mediation analyses to evaluate associations and inflammatory pathways.

Main Results:

  • Higher FTUs were associated with reduced all-cause mortality (HR=0.73) and showed a trend for cardiovascular mortality.
  • Systemic inflammation indices partially mediated the association between FTUs and mortality (3.31-6.20% for all-cause, 2.17-4.27% for cardiovascular).
  • The link between masticatory function and all-cause mortality was stronger and more consistent than with cardiovascular mortality.

Conclusions:

  • Improved masticatory function is associated with better survival outcomes in stroke patients.
  • Systemic inflammation partially mediates the beneficial effect of masticatory function on mortality.
  • Masticatory function, assessed by FTUs, may be a valuable prognostic tool for risk stratification in stroke populations.