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Updated: May 31, 2026

Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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Published on: November 14, 2017

The physiological effects of APOE genotype in healthy young/middle-aged individuals

Sherida M de Leeuw1,2, Sheina Emrani3, Julian Putter4

  • 1Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, 630 West 168th Street, New York, NY, 10032, USA.

Biological Reviews of the Cambridge Philosophical Society
|May 30, 2026
PubMed

Keywords:
AD biomarkersAPOEEEGMEGMRIPETSARS‐CoV‐2TBIageapolipoproteinatheroscleroticbody fat percentagebody massbrain metabolismbrain structurecholesterolcognitionconcussiondietfMRIfunctional connectivityinflammationlifestylelipidsmiddle‐agedpollutionsextraumatic brain injuryvirus infectionyoung

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