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Related Experiment Video

Updated: Jun 1, 2026

A Dorsal Skinfold Window Chamber Tumor Mouse Model for Combined Intravital Microscopy and Magnetic Resonance Imaging in Translational Cancer Research

A Dorsal Skinfold Window Chamber Tumor Mouse Model for Combined Intravital Microscopy and Magnetic Resonance Imaging in Translational Cancer Research

Published on: April 12, 2024

Multimodality Cardiac Imaging and Multidisciplinary Collaboration in Monitoring Intracardiac Sarcoma Response to

Christopher Kocx¹, Lucy Geraghty¹, Zara Rolfe¹

¹Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.

JACC. Case Reports

|May 30, 2026

Summary

Intracardiac tumors causing obstruction can be safely treated with immune checkpoint inhibitors (ICI). Multimodality imaging is crucial for monitoring treatment response and avoiding pseudoprogression in these rare cases.

Area of Science:

Cardio-oncology
Advanced cardiac imaging
Oncologic therapeutics

Background:

Intracardiac metastases causing right ventricular outflow tract obstruction are rare and associated with a poor prognosis.

Keywords:

alveolar soft part sarcoma cardiac magnetic resonance cardio-oncology immunotherapy intracardiac metastasis right ventricular outflow tract obstruction

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Immune checkpoint inhibitor (ICI) therapy poses a risk of immune-mediated pseudoprogression, potentially exacerbating hemodynamic compromise.