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Fascioliasis presenting as non-resolving liver abscess: Case series from eastern India
Ayan Basu1, Dipankar Paul2, Yogiraj Ray1
1Associate Professor, Department of Infectious Diseases, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India.
Fascioliasis, a foodborne liver fluke infection, is rarely reported in India. This study details six acute cases diagnosed via diet, imaging, and stool analysis, successfully treated with antiparasitic drugs.
Area of Science:
- Medicine
- Parasitology
- Infectious Diseases
Background:
- Fascioliasis is a foodborne parasitic disease caused by Fasciola hepatica and Fasciola gigantica.
- It is transmitted through the ingestion of contaminated aquatic vegetation containing metacercariae.
- The infection presents with acute symptoms like fever and abdominal pain, and chronic symptoms related to biliary obstruction.
Purpose of the Study:
- To report and characterize recent cases of fascioliasis in India.
- To highlight diagnostic methods for acute fascioliasis.
- To present treatment outcomes for diagnosed cases.
Main Methods:
- Retrospective analysis of six fascioliasis cases presenting with acute symptoms over one year.
- Diagnosis based on dietary history, liver abscess identification via imaging, and detection of Fasciola eggs in stool.
- Treatment with Triclabendazole or Nitazoxanide.
Main Results:
- Six cases of acute fascioliasis were diagnosed in India, a region with infrequent reports.
- Characteristic dietary history, imaging findings of liver abscesses, and stool examination confirmed the diagnosis.
- All patients responded well to treatment with Triclabendazole or Nitazoxanide.
Conclusions:
- Fascioliasis, though uncommon, should be considered in the differential diagnosis of patients with relevant symptoms in India.
- Prompt diagnosis through a combination of clinical, dietary, imaging, and parasitological methods is crucial.
- Antiparasitic treatment with Triclabendazole or Nitazoxanide is effective for acute fascioliasis.
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