Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 1, 2026

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

Conserved dopaminergic system in Octopus minor: molecular characterization and spatial expression.

Chan-Jun Lee¹, Kyoung-Bin Ryu¹, Hae-Youn Lee¹

¹Department of Biological Sciences and Biotechnology, College of Natural Sciences, Chungbuk National University, Cheongju, Chungcheongbuk-do, 28644, Republic of Korea.

Brain Structure & Function

|May 30, 2026

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Transcriptomic analysis reveals functional compartmentalization of the digestive tract in Urechis unicinctus.

Genes & genomics·2026

Same author

Insights into cephalochordate genome and gene evolution from the early-diverging amphioxus <i>Asymmetron lucayanum</i>.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Notch signaling in leech neurogenesis: expression patterns and functional insights in the Glossiphoniid leech <i>Helobdella austinensis</i>.

Animal cells and systems·2026

Same author

Integrated morphological and transcriptomic analysis of sucker development in <i>Octopus minor</i>.

Animal cells and systems·2026

Same author

Transcriptome-based screening of regulator genes for sexual dimorphism in pupae of Callipogon relictus.

Genes & genomics·2025

Same author

Temporal Regulation of Cytokines and Growth Factors for Optimized Hematopoietic-Lineage Specification from Human Pluripotent Stem Cells.

International journal of stem cells·2025

The study reveals that the dopamine biosynthesis pathway and related functions are conserved in Octopus minor, with key genes expressed in specific brain regions. This neurotransmitter system shows evolutionary conservation in cephalopods.

Area of Science:

Neuroscience
Evolutionary Biology
Biochemistry

Background:

Dopamine is a crucial neurotransmitter with a conserved pathway and receptor system across bilaterians.
Evidence suggests dopamine's origin predates bilaterian diversification.
Dopaminergic genes and biosynthesis pathway components are known in cephalopods, but detailed analyses are lacking.

Purpose of the Study:

To investigate the sequence features and neural expression patterns of dopamine biosynthesis and receptor systems in Octopus minor.
To determine the evolutionary conservation of dopamine pathways in cephalopods.

Main Methods:

Bioinformatics analysis of dopamine synthesis and receptor systems.
Phylogenetic analysis to identify dopamine-related gene sequences.

Keywords:

Brain Classical biosynthesis pathway Dopamine Mollusca Receptor

More Related Videos

Dissection and Culture of Mouse Dopaminergic and Striatal Explants in Three-Dimensional Collagen Matrix Assays

Dissection and Culture of Mouse Dopaminergic and Striatal Explants in Three-Dimensional Collagen Matrix Assays

Published on: March 23, 2012

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

Related Experiment Videos

Last Updated: Jun 1, 2026

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Establishing an Octopus Ecosystem for Biomedical and Bioengineering Research

Published on: September 22, 2021

Dissection and Culture of Mouse Dopaminergic and Striatal Explants in Three-Dimensional Collagen Matrix Assays

Dissection and Culture of Mouse Dopaminergic and Striatal Explants in Three-Dimensional Collagen Matrix Assays

Published on: March 23, 2012

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Mining Spatial Transcriptomics Datasets using DeepSpaceDB

Published on: September 5, 2025

Analysis of gene expression patterns in the Octopus minor brain.

Main Results:

Dopamine synthesis and receptor systems are associated with the Supraesophageal mass and optic lobe.
Two classical dopamine biosynthesis genes were commonly expressed in the granular layer, basal lobe, and anterior buccal lobe.
Two types of dopamine receptors exhibited distinct expression patterns in the brain and optic lobe.

Conclusions:

The classical dopamine biosynthesis pathway is conserved in Octopus minor.
Several dopamine-related functions appear conserved in Octopus minor, indicating evolutionary stability of this neurotransmitter system.