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Foraging crumbles reduce severe aggression in laboratory mice.

Marie B Bennett1, Aaron B Booth2, Erin Q Murdoch2

  • 1George Mason University, Fairfax, VA, United States; University of Texas at San Antonio Health Science Center, San Antonio, TX, United States.

Physiology & Behavior
|May 30, 2026
PubMed
Summary
This summary is machine-generated.

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Foraging crumbles in laboratory mouse cages reduced severe aggression and injury. These crumbles did not interfere with cognitive, anxiety, or circadian rhythm testing in mice.

Area of Science:

  • Laboratory animal science
  • Animal behavior

Background:

  • Foraging crumbles are used to reduce aggression in laboratory mice.
  • The effects of foraging crumbles on mouse aggression and behavior are not well-studied.

Purpose of the Study:

  • To investigate the impact of foraging crumbles on aggression in male laboratory mice.
  • To determine if crumbles decrease, increase, or have no effect on aggression.
  • To assess potential interference with behavioral assays.

Main Methods:

  • Male laboratory mice were housed with foraging crumbles.
  • Aggression levels, including injurious aggression, were monitored.
  • Behavioral assays for cognitive function, anxiety, and circadian rhythms were conducted at 100 days.
Keywords:
AggressionEnrichmentHousingMouse

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Main Results:

  • Foraging crumbles were associated with a significant decrease in severe aggression and injury.
  • No significant interference was observed in cognitive, anxiety, or circadian rhythm assays.
  • The study provides initial evidence for the efficacy of foraging crumbles in mitigating aggression.

Conclusions:

  • Foraging crumbles can be a useful tool for reducing aggression in laboratory mice without compromising behavioral research.
  • Further research is warranted to explore the long-term effects and optimal implementation of foraging crumbles.