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Metastatic breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

E de Azambuja1, C H Barrios2, R Bartsch3

  • 1Medical Oncology Department, Institut Jules Bordet, Hôpital Universitaire de Bruxelles (H.U.B), Université Libre de Bruxelles (U.L.B), Brussels, Belgium.

Annals of Oncology : Official Journal of the European Society for Medical Oncology
|May 30, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
de novo diseasediagnosisguidelinemetastatic breast cancer (MBC)oligometastatictreatment

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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