Related Experiment Video
Updated: Jun 1, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
Pilot Randomized Trial of a Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer
Kelsey S Lau-Min1, Riley Psenka2, Mia Holtze3
1Division of Hematology/Oncology (K.S.L.M., A.H., A.P., A.E.J., J.S.T.), Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA; Cancer Outcomes Research and Education Program (K.S.L.M., C.M., S.B.L., R.N., A.E.J., J.S.T., L.T.), Massachusetts General Hospital Cancer Center, Boston, Massachusetts, USA.
The PATHWAYS intervention, an educational guide with coaching, proved feasible and acceptable for patients undergoing lengthy locally advanced rectal cancer (LARC) treatment. High engagement suggests its value in supportive cancer care.
Area of Science:
- Oncology
- Patient Support
- Clinical Trials
Background:
- Multimodality therapy for locally advanced rectal cancer (LARC) presents significant challenges for patients.
- A novel intervention, PATHWAYS, was developed to provide informational and supportive care during LARC treatment.
Purpose of the Study:
- To evaluate the feasibility and acceptability of the PATHWAYS intervention.
- To gather patient feedback for refining the PATHWAYS intervention.
Main Methods:
- A pilot randomized controlled trial (RCT) comparing PATHWAYS to enhanced usual care.
- Participants received an educational guide and behavioral coaching or online resources.
- Feasibility and acceptability were primary outcomes, assessed via enrollment, completion rates, and patient satisfaction questionnaires.
Main Results:
- 59% of eligible patients enrolled in the pilot study.
- 90% of patients receiving the PATHWAYS intervention completed it, with 100% reporting acceptability.
- Qualitative feedback indicated the guide enhanced knowledge and coaching made learning manageable.
Conclusions:
- The PATHWAYS intervention demonstrated high engagement and acceptability in patients with LARC.
- Findings support the refinement of PATHWAYS for improved supportive care in complex cancer treatments.
Related Concept Videos
Treatment Resistent Cancers
Treatment Resistant Cancers