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Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...

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Updated: Jun 1, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Optical coherence tomography angiography: Principles and applications.

Tristan T Hormel1, Yali Jia2

  • 1Casey Eye Institute, Oregon Health & Science University, Portland, OR, United States.

Handbook of Clinical Neurology
|May 30, 2026
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography angiography (OCTA) enables high-resolution, noninvasive imaging of retinal microvasculature, overcoming limitations of structural OCT. This technology visualizes capillaries and pathology, advancing ophthalmic diagnostics.

Keywords:
B-scansOptical coherence tomography angiographyOptical microangiographySplit-spectrum amplitude-decorrelationVascular anatomy

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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

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Last Updated: Jun 1, 2026

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
08:50

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography

Published on: February 9, 2019

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Area of Science:

  • Ophthalmology
  • Biomedical Imaging
  • Medical Technology

Background:

  • Structural Optical Coherence Tomography (OCT) provides high-resolution retinal imaging but cannot visualize capillaries due to low contrast.
  • Microvascular imaging is crucial for understanding retinal health and disease.

Purpose of the Study:

  • To explain the principles and applications of OCT angiography (OCTA) for retinal microvascular imaging.
  • To detail the capabilities of OCTA in visualizing retinal vascular anatomy, pathology, and quantitative analysis.

Main Methods:

  • OCTA generates motion contrast images by acquiring sequential scans at a single location, using blood flow as an intrinsic contrast agent.
  • Discussion includes signal generation algorithms, vascular anatomy, common pathologies, and advanced quantification techniques like AI-based image processing.

Main Results:

  • OCTA overcomes the resolution-contrast limitation of structural OCT, enabling capillary-level vascular imaging.
  • It allows for volumetric imaging of retinal circulation and detailed visualization of vascular morphology and structure.
  • Common pathologic features and their measurements using OCTA are discussed, including AI-driven quantification.

Conclusions:

  • OCTA is a powerful tool for noninvasive, high-resolution imaging of the retinal microvasculature.
  • It complements structural OCT by providing functional vascular information, aiding in disease diagnosis and research.
  • Future advancements in OCTA technology promise further improvements in ophthalmic diagnostics and treatment monitoring.