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Updated: Jun 1, 2026

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
09:01

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli

Published on: March 16, 2011

Beyond natural evolution: multi-scale in vivo mutagenesis toolkits for synthetic evolution

Zhijun Teng1, Julian E Prieto-Vivas2, Kevin J Verstrepen3

  • 1State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China; Haihe Laboratory of Synthetic Biology, Tianjin 300308, China; University of Chinese Academy of Sciences, Beijing 100049, China; National Center of Technology Innovation for Synthetic Biology, Tianjin 300308, China; TIB - VIB Joint Center of Synthetic Biology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.

Trends in Biotechnology
|May 30, 2026
PubMed

Keywords:
evolutionary engineeringin vivo mutagenesismutational scalesynthetic biologysynthetic evolution

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