[Wellens syndrome and U-wave inversion during angina]
János Tomcsányi1, Tamás Frész1, Marcell Csákányi1
11 Betegápoló Irgalmasrend Budai Irgalmasrendi Kórháza, Kardiológia Budapest, Árpád fejedelem u. 7. II. em., 1023 Magyarország.
Orvosi Hetilap
|May 31, 2026
Summary
This case study highlights distinct recovery patterns of ischemic repolarization abnormalities. Negative U-waves resolved post-intervention, but Wellens syndrome T-wave changes persisted, indicating differential myocardial responses.
Area of Science:
- Cardiology
- Clinical Electrocardiography
- Ischemic Heart Disease
Background:
- Wellens syndrome is characterized by specific ECG findings indicating critical coronary stenosis.
- U-wave abnormalities on ECG can also signify cardiac pathology, including ischemia.
Purpose of the Study:
- To describe a unique case of ischemic repolarization disorders with differential resolution patterns.
- To analyze the distinct dynamics of U-wave and T-wave changes in response to intervention.
Main Methods:
- Case report of a patient with chest pain and ECG abnormalities.
- Performance of coronary angiography and percutaneous coronary intervention (PCI).
- Serial electrocardiogram (ECG) monitoring to assess repolarization changes.
Main Results:
- Admission ECG showed deep negative U-waves and T-wave inversions in precordial leads (Wellens syndrome).
- Post-PCI for left anterior descending artery stenosis, U-wave inversion resolved.
- Wellens syndrome T-wave abnormalities persisted despite successful revascularization.
Conclusions:
- Ischemic repolarization disorders, like U-wave and T-wave changes, can exhibit different recovery dynamics.
- Persistence of Wellens syndrome findings post-intervention warrants further investigation into underlying mechanisms.
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