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Comparative Analysis of Anterior Segment Biometry: Agreement and Correlation Between Swept-Source OCT and
Eun Hye Jung1, Hyunjo Lee2, Tae-Im Kim3
1Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Korean Journal of Ophthalmology : KJO
|May 31, 2026
Summary
Anterior keratometry and central corneal thickness measurements showed excellent agreement between three devices, but total keratometry, pupil diameter, and white-to-white measurements were not interchangeable. Consistent device use is crucial for accurate clinical decisions.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Optometry
Background:
- Accurate anterior segment biometry is essential for ophthalmic procedures.
- Comparing measurement agreement across different devices is critical for clinical practice.
Purpose of the Study:
- To evaluate inter-device agreement for keratometry, central corneal thickness (CCT), pupil diameter (PD), and white-to-white (WTW) measurements.
- To compare three leading anterior segment biometers: Anterion, Pentacam HR, and IOLMaster 700.
Main Methods:
- Retrospective analysis of 165 eyes from 88 patients.
- Measurements of anterior/total keratometry, CCT, PD, and WTW using all three devices.
- Statistical analysis included ANOVA, ICC, Bland-Altman, and Deming regression.
Main Results:
- Excellent agreement (ICC ≥0.96) for anterior keratometry (SimK) and CCT with minimal bias.
- Significant discrepancies observed in total keratometry, PD, and WTW measurements.
- Deming regression indicated proportional bias in total keratometry and constant bias in CCT and PD.
Conclusions:
- While SimK and CCT show high statistical agreement, they are not interchangeable.
- Clinical relevance highlighted for cataract surgery, refractive surgery planning, and corneal disease diagnosis.
- Emphasizes the need for consistent device usage or validated conversion methods.
