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Comparative Analysis of Anterior Segment Biometry: Agreement and Correlation Between Swept-Source OCT and
Eun Hye Jung1, Hyunjo Lee2, Tae-Im Kim3
1Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose:
To evaluate the inter-device agreement of keratometry, central corneal thickness (CCT), pupil diameter (PD), and white-to-white (WTW) measurements among three anterior segment biometers: Anterion, Pentacam HR, and IOLMaster 700.
Methods:
This retrospective study analyzed 165 eyes of 88 patients who underwent measurements using all three devices on the same day under standardized mesopic illumination. Parameters included anterior and total keratometry, CCT, PD, and WTW. Agreement was assessed using repeated-measures ANOVA, intraclass correlation coefficient (ICC), Bland-Altman analysis, and Deming regression.
Results:
Anterior keratometry (SimK) and CCT showed excellent agreement (ICC ≥0.96) with minimal bias (<0.2 D and <8 µm, respectively). The IOLMaster 700 measured slightly steeper keratometry and thinner corneas than the Anterion, whereas the Pentacam yielded thicker CCT values. Total keratometry exhibited larger discrepancies than anterior keratometry. The Anterion reported smaller WTW measurements than the IOLMaster 700. Deming regression revealed proportional bias in total keratometry and constant bias in CCT and PD across the three devices.
Conclusions:
Although SimK and CCT showed a strong statistical agreement, they were not found to be fully interchangeable. The need for consistent use of devices or validated conversion methods in clinical settings is emphasized by the significant differences in total keratometry, PD, and WTW. These findings are clinically relevant for proper cataract surgery, refractive surgery planning, and diagnosis of corneal diseases.
