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Updated: Jun 2, 2026

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Idiopathic Multicentric Castleman Disease Presenting as Recurrent Acute-Onset Demyelinating Neuropathy

Chisato Saito1, Yumi Honda1, Hironori Mizutani1

  • 1Department of Neurology, Kumamoto University Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|May 31, 2026
PubMed
Summary

This case study describes a rare instance of acute, severe motor-predominant polyneuropathy in a patient diagnosed with idiopathic multicentric Castleman disease (iMCD). The findings highlight the potential role of interleukin-6 (IL-6) in iMCD-associated neuropathy.

Keywords:
Castleman diseasedemyelinating neuropathyinterleukin-6polyneuropathy

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