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Related Experiment Video

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Multidimensional Optimization of Small Bowel Capsule Endoscopy With Transcutaneous Electrical Acustimulation: A

Yi Long Liu1, Bei Fang Ning1, Ya Nan Mao1

  • 1Department of Gastroenterology, Changzheng Hospital, Naval Medical University, Shanghai, China.

Journal of Digestive Diseases
|June 1, 2026
PubMed
Summary
This summary is machine-generated.

Transcutaneous electrical acustimulation (TEA) significantly improves small bowel capsule endoscopy (SBCE) preparation by reducing adverse events and improving visualization. This safe technique enhances patient comfort and acceptability during the procedure.

Keywords:
bowel preparationgastrointestinal motilityneuromodulationsmall bowel capsule endoscopytranscutaneous electrical acustimulation

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Area of Science:

  • Gastroenterology
  • Endoscopy
  • Acupuncture and Electrotherapy

Background:

  • Small bowel capsule endoscopy (SBCE) is a crucial diagnostic tool.
  • Bowel preparation for SBCE can be associated with gastrointestinal adverse events (AEs).
  • Optimizing SBCE preparation is essential for diagnostic yield and patient experience.

Purpose of the Study:

  • To evaluate the efficacy of transcutaneous electrical acustimulation (TEA) during SBCE bowel preparation.
  • To assess TEA's impact on gastrointestinal AEs, gastric transit time (GTT), visualization quality, and patient acceptability.

Main Methods:

  • Prospective randomized controlled trial involving outpatients scheduled for SBCE.
  • Participants received either TEA at ST36 acupoints or sham stimulation during split-dose polyethylene glycol bowel preparation.
  • Primary outcome: incidence of gastrointestinal AEs; Secondary outcomes: AE severity, visualization quality, GTT, and lesion detection.

Main Results:

  • TEA significantly reduced the overall incidence and severity of gastrointestinal AEs, including nausea and bloating (p < 0.004).
  • TEA significantly improved small bowel visualization quality scores (p = 0.003 for entire, p = 0.030 for distal).
  • TEA significantly shortened GTT (p < 0.001) and enhanced patient comfort and acceptability (p < 0.027).

Conclusions:

  • Transcutaneous electrical acustimulation (TEA) is an effective adjunct for SBCE bowel preparation.
  • TEA significantly mitigates gastrointestinal AEs, accelerates GTT, and improves visualization quality.
  • TEA is a safe, well-tolerated intervention that optimizes the SBCE procedure.