Related Experiment Video
Updated: Jun 2, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
Published on: October 14, 2025
A pilot randomized controlled trial of the self-management assistance for recommended treatment inflammatory bowel
Taylor M Dattilo1, Abigail S Robbertz1, Lee A Denson2,3
1Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Center for Adherence and Self-Management, Cincinnati, Ohio, USA.
Abstract:
We examined the use of a mobile self-management assistance for recommended treatment (SMART) inflammatory bowel disease (IBD) app to improve health outcomes compared to an attention control (AC) arm in adolescents with IBD. Thirty-five participants (M = 15 years; 48% female, 75% white) were randomly assigned to the SMART IBD app or AC arm and completed daily diaries at baseline followed by a 1-month intervention and then completed the same daily diaries at post-treatment. Results demonstrated a significant treatment by time effect for perceived stress (F = 4.32, p < 0.05) and sleep quantity (F = 7.74, p < 0.01), with participants receiving the SMART IBD app intervention reporting a significant decrease in stress and increase in average sleep quantity from baseline to post-treatment compared to the AC arm. Using the SMART IBD app may improve health outcomes important to the overall management of IBD. Trial Registration: ClinicalTrials.gov identifier: NCT06023667 (https://clinicaltrials.gov/study/NCT06023667).
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