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Identifying the Aggression Impulsive/Reactive (AIR) Profile in Youth With Behavioral Challenges.

Ekaterina Stepanova1, Joshua A Langfus2, Eric A Youngstrom3

  • 1Virginia Commonwealth University, Richmond, Virginia.

JAACAP Open
|June 1, 2026
PubMed
Summary
This summary is machine-generated.

This study identified a distinct aggression profile in youth seeking mental health services. The aggression impulsive/reactive (AIR) profile, characterized by hyperactivity and impulsivity, was validated in a clinical sample.

Keywords:
aggressionaggression impulsive/reactivechildren

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Area of Science:

  • Child and Adolescent Psychiatry
  • Developmental Psychology
  • Behavioral Science

Background:

  • Aggression in youth is a significant concern, yet its classification remains unclear.
  • Previous research identified a profile of aggression impulsive/reactive (AIR) with hyperactivity/impulsivity in youth.
  • The current study aimed to validate this AIR profile in a clinical population.

Purpose of the Study:

  • To determine if the aggression impulsive/reactive (AIR) profile is present in a clinical sample of children and adolescents.
  • To utilize novel dimensional measures and latent profile analysis to evaluate the AIR profile.
  • To compare findings with previous research on youth aggression.

Main Methods:

  • Reviewed medical records of 430 patients aged 4-17 with behavioral concerns.
  • Caregivers completed dimensional measures of aggression, mania, depression, and hyperactivity/impulsivity.
  • Latent profile analysis was used to identify symptom clusters.

Main Results:

  • Four distinct profiles were identified, including a predominant AIR profile with hyperactivity-impulsivity.
  • Children with high AIR and hyperactivity-impulsivity were younger, male, and had earlier onset of aggression.
  • This subgroup was less likely to have a history of abuse.

Conclusions:

  • The aggression impulsive/reactive (AIR) profile is validated in a new cohort of clinically referred youth.
  • Findings support the existence of a distinct AIR profile in pediatric mental health settings.
  • Further research is needed to develop diagnostic criteria for children with AIR.