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Feasibility and Safety of a Computer-Controlled Device for Transradial Cerebral Angiography: A Prospective Pilot
Shun Tanaka1,2, Koji Hirata1, Koichi Uramaru1
1Department of Stroke and Cerebrovascular Diseases, University of Tsukuba Hospital, Tsukuba, Ibaraki, Japan.
Journal of Neuroendovascular Therapy
|June 1, 2026
Summary
Computer-controlled local anesthesia proved feasible and safe for transradial cerebral angiography in a pilot study. This innovative device facilitated successful procedures with minimal patient discomfort and no access-site complications.
Area of Science:
- Neurology
- Interventional Radiology
- Anesthesiology
Background:
- Transradial access is a common approach for cerebral angiography.
- Effective local anesthesia is crucial for patient comfort and procedural success.
- Traditional local anesthetic delivery can be variable.
Purpose of the Study:
- To assess the feasibility and safety of a computer-controlled local anesthetic delivery device during transradial cerebral angiography.
- To descriptively evaluate procedural pain and hemodynamic changes associated with the device.
Main Methods:
- A prospective pilot study involving 10 adult patients undergoing elective diagnostic cerebral angiography.
- Local anesthesia was administered using a computer-controlled device with 3% mepivacaine via a 33-G needle.
- Feasibility was defined by successful anesthesia delivery and transradial access completion without complications. Pain was assessed using a visual analogue scale (VAS), and hemodynamic parameters were monitored.
Main Results:
- All 10 procedures were successfully completed using the computer-controlled device without malfunction or need for conversion to manual injection.
- The median VAS scores for pain were low across procedural steps (anesthesia, puncture, sheath insertion).
- No significant changes in systolic or diastolic blood pressure were observed, and no access-site complications like vasospasm or bleeding occurred.
Conclusions:
- Computer-controlled local anesthesia is a feasible and safe option for transradial cerebral angiography in this initial patient cohort.
- The descriptive pain and hemodynamic findings suggest potential benefits, warranting further investigation.
- Larger, controlled studies are needed to confirm the efficacy of this technology.

